The link between obesity and psoriatic arthritis

Psoriatic arthritis (PsA) is classified as a spondyloarthropathy and is characterised by synovitis, enthesitis, dactylitis and spondylitis, usually following the development of cutaneous and nail psoriasis.1 PsA patients have a higher prevalence of some comorbidities (obesity, metabolic syndrome, depression and premature cardiovascular disease) than patients with psoriasis (Pso) without arthritis.2 Increased adiposity and weight gain have been associated with the risk of psoriasis in a prospective study,3 and because 10–30% of Pso patients develop PsA, it is increasingly important to determine whether obesity is solely a comorbid condition in PsA or a risk factor. A case–control study in patients with Pso found that patient-reported body mass index (BMI) at age 18 years, b...

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