Physiological role of a novel hormone FNDC5/irisin revealed in humans

Scientists have elucidated the molecular and clinical role of FNDC5/irisin in humans. Irisin is a recently identified hormone secreted from muscle cells that has been found to serve as a chemical messenger providing key exercise-induced health benefits in mice. In these earlier studies, irisin showed direct effects on ?browning? of white fat which would lead to burning of excess calories. Discovery of irisin therefore raised expectations of potential for developing new therapies for metabolic diseases.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/fitness/~3/959XcqHYXEc/121001083542.htm

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