Even with a greater muscle mass, a sprinter cannot win a marathon. His specially-trained and strengthened muscles will fatigue faster than the endurance-trained muscles of a long distance runner. Medical researchers have now shown that during endurance exercise the protein PGC-1alpha shifts the metabolic profile in the muscle.
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Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/fitness/~3/LfcDMoELUnw/130514112751.htm
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