Wednesday 6 February 2013

Dysglycaemia in the critically ill ? significance and management

Abstract
Hyperglycaemia frequently occurs in the critically ill, in patients with diabetes, as well as those who were previously glucose?tolerant. The terminology ?stress hyperglycaemia? (SH) reflects the pathogenesis of the latter group, which may comprise up to 40% of critically ill patients. For comparable glucose concentrations during acute illness outcomes in SH appear to be worse than those in patients with type 2 diabetes. While several studies have evaluated the optimum glycaemic range in the critically ill, their interpretation in relation to clinical recommendations is somewhat limited, at least in part because patients with SH and known diabetes were grouped together, and the optimum glycaemic range was regarded as static, rather than dynamic, phenomenon. In addition to hy...

Source: http://www.medworm.com/index.php?rid=7013926&cid=u_0_15_f&fid=33011&url=http%3A%2F%2Fonlinelibrary.wiley.com%2Fresolve%2Fdoi%3FDOI%3D10.1111%252Fdom.12078

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